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Nuclear Receptor Corepressor 1 (NCOR1) Antibody
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Catalogue No: abx011240
Price:
US$427.75
(Size: 100 µl)
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NCOR1: Nuclear receptor co-repressor 1. This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Research Articles on Nuclear Receptor Corepressor 1 (NCOR1)
| Target | Nuclear Receptor Corepressor 1 (NCOR1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O75376 (UniProt, ExPASy) |
| UniProt Secondary AC | B3DLF8, E9PGV6, Q86YY0, Q9UPV5, Q9UQ18 |
| UniProt Entry Name | NCOR1_HUMAN |
| Gene Symbol | NCOR1 |
| GeneID | 9611 |
| OMIM | 600849 |
| HGNC | 7672 |
| KEGG | hsa:9611 |
| Ensembl | ENSG00000141027 |
| String | 9606.ENSP00000268712 |
| Molecular Weight | 270 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |