NADH Ubiquinone Oxidoreductase Core Subunit S1 (NDUFS1) Antibody

NDUFS1 Antibody is a Rabbit Polyclonal antibody against NDUFS1. The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

Target	NADH Ubiquinone Oxidoreductase Core Subunit S1 (NDUFS1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 80-290 of human NDUFS1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P28331 (UniProt, ExPASy)
UniProt Entry Name	NDUS1_HUMAN
Gene Symbol	NDUFS1
GeneID	4719
NCBI Accession	NP_004997.4
KEGG	hsa:4719
String	9606.ENSP00000392709
Molecular Weight	Calculated MW: 79 kDa Observed MW: 79 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NADH Ubiquinone Oxidoreductase Core Subunit S1 (NDUFS1)

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