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NADH:Ubiquinone Oxidoreductase Core Subunit S8 (NDUFS8) Antibody
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Catalogue No: abx026882
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
Reviews: 
(1 Publications and Reviews)
(1 Publications and Reviews)
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This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.
Research Articles on NADH:Ubiquinone Oxidoreductase Core Subunit S8 (NDUFS8)
| Target | NADH:Ubiquinone Oxidoreductase Core Subunit S8 (NDUFS8) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 81-108 amino acids from the Central region of human NDUFS8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O00217 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RB86, Q0VDA8 |
| UniProt Entry Name | NDUS8_HUMAN |
| Gene Symbol | NDUFS8 |
| GeneID | 4728 |
| OMIM | 602141 |
| HGNC | 7715 |
| KEGG | hsa:4728 |
| Ensembl | ENSG00000110717 |
| String | 9606.ENSP00000315774 |
| Molecular Weight | Calculated MW: 23.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Cow, Monkey, Drosophila and C. elegans NDUFS8. |
| Concentration | 0.48 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |