Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin (NEDD4) Antibody
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Catalogue No: abx000756
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US$348.00
(Size: 60 µl)
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NEDD4 Antibody is a Rabbit Polyclonal antibody against NEDD4. NEDD4-1(Neural precursor cell expressed developmentally down-regulated protein 4) is also named as NEDD4 and KIAA0093. It plays an essential role for the activation of the genetic program involved in the terminal maturation stage of invariant natural killer T-cell development(PMID:21949387). And it is differentially expressed in mammary epithelial cells and plays a role in luminal lineage determination(PMID:20351249). NEDD4-1 is a key regulator of FGFR1 endocytosis and signalling during neuronal differentiation and embryonic development(PMID:21765395). This antibody can recognize NEDD4-1 and NEDD4-2.
Research Articles on Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin (NEDD4)
| Target | Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin (NEDD4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human NEDD4 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P46934 (UniProt, ExPASy) |
| UniProt Entry Name | NEDD4_HUMAN |
| Gene Symbol | NEDD4 |
| GeneID | 4734 |
| NCBI Accession | NP_940682.2 |
| KEGG | hsa:4734 |
| String | 9606.ENSP00000424827 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
