Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin (NEDD4) Antibody

Catalogue No: abx000756
Price: £120.00
(Size: 20 µl)
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NEDD4 Antibody is a Rabbit Polyclonal antibody against NEDD4. NEDD4-1(Neural precursor cell expressed developmentally down-regulated protein 4) is also named as NEDD4 and KIAA0093. It plays an essential role for the activation of the genetic program involved in the terminal maturation stage of invariant natural killer T-cell development(PMID:21949387). And it is differentially expressed in mammary epithelial cells and plays a role in luminal lineage determination(PMID:20351249). NEDD4-1 is a key regulator of FGFR1 endocytosis and signalling during neuronal differentiation and embryonic development(PMID:21765395). This antibody can recognize NEDD4-1 and NEDD4-2.

Target NEDD4
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 160-460 of human NEDD4.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P46934 (UniProt, ExPASy)
UniProt Entry Name NEDD4_HUMAN
Gene Symbol NEDD4
GeneID 4734
NCBI Accession NP_940682.2
KEGG hsa:4734
String 9606.ENSP00000424827
Molecular Weight Calculated MW: 104 kDa, 140 kDa, 147 kDa, 149 kDa
Observed MW: 120 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 2.61 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin (NEDD4) Antibody

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