Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) Antibody

NEDD9 Antibody is a Rabbit Polyclonal antibody against NEDD9. The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.

Target	Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 390-560 of human NEDD9.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14511 (UniProt, ExPASy)
UniProt Secondary AC	A8K9G7, A8MSJ9, G5E9Y9, Q5T9R4, Q5XKI0
UniProt Entry Name	CASL_HUMAN
Gene Symbol	NEDD9
GeneID	4739
NCBI Accession	NP_006394.1
KEGG	hsa:4739
String	9606.ENSP00000368759
Molecular Weight	Calculated MW: 93 kDa Observed MW: 105 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9)

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