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Neurofilament, Light Polypeptide (NEFL) Antibody

Catalogue No: abx000642
Price: £95.00
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Neurofilament, Light Polypeptide (NEFL) Antibody Neurofilament, Light Polypeptide (NEFL) Antibody Neurofilament, Light Polypeptide (NEFL) Antibody Neurofilament, Light Polypeptide (NEFL) Antibody

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NEFL Antibody is a Rabbit Polyclonal antibody against NEFL. Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Target NEFL
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human NEFL.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UNSPSC Code 12352203
UniProt Primary AC P07196
Gene Symbol NEFL
GeneID 4747
Molecular Weight Calculated MW: 61 kDa
Observed MW: 82 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Neurofilament, Light Polypeptide (NEFL) Antibody

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