Negative Elongation Factor Complex Member E (NELFE) Antibody

NELFE Antibody is a Rabbit Polyclonal antibody against NELFE. The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.

Target	Negative Elongation Factor Complex Member E (NELFE)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human NELFE.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P18615 (UniProt, ExPASy)
UniProt Secondary AC	A2BE08, B4DUN1, B4DYX9, Q5JP74, Q5JP75, Q96F56, Q9NPK2
UniProt Entry Name	NELFE_HUMAN
Gene Symbol	NELFE
GeneID	7936
NCBI Accession	NP_002895.3
KEGG	hsa:7936
String	9606.ENSP00000364578
Molecular Weight	Calculated MW: 43 kDa Observed MW: 43 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Negative Elongation Factor Complex Member E (NELFE)

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