Netrin Receptor UNC5A (UNC5A) Antibody
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Catalogue No: abx219255
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US$420.50
(Size: 100 µg)
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Datasheet SDS
Netrin Receptor UNC5A (UNC5A) Antibody is a Rabbit Polyclonal antibody for the detection of UNC5A. Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin. Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
Research Articles on Netrin Receptor UNC5A (UNC5A)
| Target | Netrin Receptor UNC5A (UNC5A) |
| Research Area | Epigenetics, Drug Targets |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | unc-5 homolog A |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q6ZN44 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RXE6, Q8TF26, Q96GP4 |
| UniProt Entry Name | UNC5A_HUMAN |
| Gene Symbol | UNC5A |
| GeneID | 90249 |
| OMIM | 607869 |
| HGNC | 12567 |
| KEGG | hsa:90249 |
| Ensembl | ENSG00000113763 |
| String | 9606.ENSP00000332737 |
| Molecular Weight | Observed MW: 93 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |