Netrin Receptor UNC5A (UNC5A) Antibody

Netrin Receptor UNC5A (UNC5A) Antibody is a Rabbit Polyclonal antibody for the detection of UNC5A.

Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin. Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.

Target	Netrin Receptor UNC5A (UNC5A)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	unc-5 homolog A
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q6ZN44 (UniProt, ExPASy)
UniProt Secondary AC	B2RXE6, Q8TF26, Q96GP4
UniProt Entry Name	UNC5A_HUMAN
Gene Symbol	UNC5A
GeneID	90249
OMIM	607869
HGNC	12567
KEGG	hsa:90249
Ensembl	ENSG00000113763
String	9606.ENSP00000332737
Molecular Weight	Observed MW: 93 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Netrin Receptor UNC5A (UNC5A)

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