Sialidase-1 (NEU1) Antibody

The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.

Target	Sialidase-1 (NEU1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 188-214 amino acids from the Central region of human NEU1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99519 (UniProt, ExPASy)
UniProt Entry Name	NEUR1_HUMAN
Gene Symbol	NEU1
KEGG	hsa:4758
String	9606.ENSP00000364782
Molecular Weight	Calculated MW: 45.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow NEU1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Sialidase-1 (NEU1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue