Neuronal Cell Adhesion Molecule (NRCAM) Antibody

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily.This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains.This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth.This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration.Allelic variants of this gene have been associated with autism and addiction vulnerability.Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	Neuronal Cell Adhesion Molecule (NRCAM)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IF/ICC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IF/ICC: 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human NRCAM (AA: 1192-1255) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92823 (UniProt, ExPASy)
UniProt Secondary AC	A4D0S3, E9PDA4, O15051, O15179, Q14BM2, Q9UHI3, Q9UHI4
UniProt Entry Name	NRCAM_HUMAN
Gene Symbol	NRCAM
GeneID	4897
OMIM	601581
HGNC	7994
KEGG	hsa:4897
Ensembl	ENSG00000091129
String	9606.ENSP00000368314
Molecular Weight	144 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Neuronal Cell Adhesion Molecule (NRCAM)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue