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Nuclear Factor of Activated T-Cells, Cytoplasmic 1 (NFATC1) Antibody

Catalogue No: abx001296
Price: £120.00
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NFATC1 Antibody is a Rabbit Polyclonal antibody against NFATC1. The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Target NFATC1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human NFATC1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O95644 (UniProt, ExPASy)
UniProt Entry Name NFAC1_HUMAN
Gene Symbol NFATC1
GeneID 4772
String 9606.ENSP00000389377
Molecular Weight Calculated MW: 38 kDa, 74- 88 kDa, 100-101 kDa
Observed MW: 80 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Nuclear Factor of Activated T-Cells, Cytoplasmic 1 (NFATC1) Antibody

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