Nuclear Factor of Activated T-Cells, Cytoplasmic 1 (NFATC1) Antibody

NFATC1 Antibody is a Rabbit Polyclonal antibody against NFATC1. The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Target	Nuclear Factor of Activated T-Cells, Cytoplasmic 1 (NFATC1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of NFAT2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95644 (UniProt, ExPASy)
UniProt Entry Name	NFAC1_HUMAN
Gene Symbol	NFATC1
GeneID	4772
NCBI Accession	NP_765978.1
KEGG	hsa:4772
String	9606.ENSP00000389377
Molecular Weight	Calculated MW: 101 kDa Observed MW: 101 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nuclear Factor of Activated T-Cells, Cytoplasmic 1 (NFATC1)

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