Nuclear Factor of Activated T-Cells, Cytoplasmic 2 (NFATC2) Antibody

NFATC2 Antibody is a Rabbit Polyclonal antibody against NFATC2. This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Target	Nuclear Factor of Activated T-Cells, Cytoplasmic 2 (NFATC2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NFATC2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13469 (UniProt, ExPASy)
UniProt Entry Name	NFAC2_HUMAN
Gene Symbol	NFATC2
GeneID	4773
NCBI Accession	NP_775114.1
KEGG	hsa:4773
String	9606.ENSP00000379330
Molecular Weight	Calculated MW: 100 kDa Observed MW: 140 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nuclear Factor of Activated T-Cells, Cytoplasmic 2 (NFATC2)

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