Nuclear Factor, Erythroid 2 (NFE2) Antibody

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Target	Nuclear Factor, Erythroid 2 (NFE2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 312-340 amino acids from the C-terminal region of human NFE2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16621 (UniProt, ExPASy)
UniProt Secondary AC	Q07720, Q6ICV9
UniProt Entry Name	NFE2_HUMAN
KEGG	hsa:4778
String	9606.ENSP00000439120
Molecular Weight	Calculated MW: 41.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nuclear Factor, Erythroid 2 (NFE2)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue