Nuclear Factor 1 A-Type (NFIA) Antibody

NFIA Antibody is a Rabbit Polyclonal antibody against NFIA. The NFI (nuclear factor I) family consists of four members in vertebrates (NFI-A, NFI-B, NFI-C and NFI-X), and the four NFI genes are expressed in unique patterns during mouse embryogenesis and in the adult. Four isoforms of NFIA were found in human and they play various roles in DNA replication, DNA-dependent transcritpion via their DNA binding property. Multiple residues of NFIA can be phosphorylated resulting in mild shifts of its practical molecular weight. Recent finding also revealed its neuroprotective function in NMDA-induced neuronal damage. Catalog# 11750-1-AP is a rabbit polyclonal antibody raised against N-terminal of human original NFIA.

Target	Nuclear Factor 1 A-Type (NFIA)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000, IHC-P: 1/50 - 1/200, IF 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 180-330 of human NFIA.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q12857 (UniProt, ExPASy)
UniProt Secondary AC	B4DRJ3, B4DS53, F5H0R0, F8W8W3, Q8TA97, Q9H3X9, Q9P2A9
UniProt Entry Name	NFIA_HUMAN
Gene Symbol	NFIA
GeneID	4774
NCBI Accession	NP_005586.1
KEGG	hsa:4774
String	9606.ENSP00000360231
Molecular Weight	Calculated MW: 56 kDa Observed MW: 60 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nuclear Factor 1 A-Type (NFIA)

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