NFKB1 (pS893) Antibody

Catalogue No: abx000462
Price: £230.00
(Size: 50 µl)

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Datasheet SDS
NFKB1 (pS893) Antibody is a Rabbit Polyclonal antibody against NFKB1 (pS893). This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

Target NFKB1 (pS893)
Clonality Polyclonal
Reactivity Human
Tested Applications IHC, IF/ICC
Host Rabbit
Recommended dilutions IHC: 1/50 - 1/200, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S893 of human NFKB1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P19838 (UniProt, ExPASy)
UniProt Secondary AC A8K5Y5, B3KVE8, Q68D84, Q86V43, Q8N4X7, Q9NZC0
UniProt Entry Name NFKB1_HUMAN
Gene Symbol NFKB1
GeneID 4790
KEGG hsa:4790
String 9606.ENSP00000226574
Molecular Weight Calculated MW: 85 kDa, 105 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on NFKB1 (pS893)

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