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NFKB1 (pS927) Antibody is a Rabbit Polyclonal antibody against NFKB1 (pS927). This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on NFKB1 (pS927) Antibody
||WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
||Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S927 of human NFKB1.
||Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
|UniProt Primary AC
||Calculated MW: 85 kDa, 105 kDa
Observed MW: 105 kDa
||PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
||> 1 mg/ml
||Shipped within 5-10 working days.
||This product is for research use only.