Nuclear Factor NF-Kappa-B P100 Subunit (NFKB2) Antibody

NFKB2 Antibody is a Rabbit Polyclonal antibody against NFKB2. This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.

Target	Nuclear Factor NF-Kappa-B P100 Subunit (NFKB2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 690-899 of human NF-κB2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q00653 (UniProt, ExPASy)
UniProt Secondary AC	A8K9D9, D3DR83, Q04860, Q9BU75, Q9H471, Q9H472
UniProt Entry Name	NFKB2_HUMAN
Gene Symbol	NFKB2
GeneID	4791
NCBI Accession	NP_002493.3
KEGG	hsa:4791
String	9606.ENSP00000358983
Molecular Weight	Calculated MW: 97 kDa Observed MW: 110 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nuclear Factor NF-Kappa-B P100 Subunit (NFKB2)

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