NF-Kappa-B Inhibitor Alpha (NFKBIA) Antibody
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Catalogue No: abx034837
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Research Articles on NF-Kappa-B Inhibitor Alpha (NFKBIA)
| Target | NF-Kappa-B Inhibitor Alpha (NFKBIA) |
| Research Area | Signal Transduction, Tumor Immunity, Hematology, Developmental Science, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified His-tagged NFKBIA protein |
| Isotype | IgG1 Kappa |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P25963 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R8L6 |
| UniProt Entry Name | IKBA_HUMAN |
| NCBI Accession | NP_065390.1 |
| KEGG | hsa:4792 |
| String | 9606.ENSP00000216797 |
| Molecular Weight | Calculated MW: 35.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |