E3 Ubiquitin-Protein Ligase NHLRC1 (NHLRC1) Antibody
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Catalogue No: abx005115
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US$217.50
(Size: 20 µl)
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Datasheet SDS
NHLRC1 Antibody is a Rabbit Polyclonal antibody against NHLRC1. The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).
Research Articles on E3 Ubiquitin-Protein Ligase NHLRC1 (NHLRC1)
| Target | E3 Ubiquitin-Protein Ligase NHLRC1 (NHLRC1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/2000 - 1/7000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to NHLRC1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q6VVB1 (UniProt, ExPASy) |
| UniProt Secondary AC | Q3SYB1, Q5VUK7, Q6IMH1 |
| UniProt Entry Name | NHLC1_HUMAN |
| Gene Symbol | NHLRC1 |
| GeneID | 378884 |
| NCBI Accession | NP_940988.2 |
| KEGG | hsa:378884 |
| String | 9606.ENSP00000345464 |
| Molecular Weight | Calculated MW: 42 kDa Observed MW: 42/45 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |