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Thyroid Transcription Factor 1 (NKX2-1) Antibody
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Catalogue No: abx002227
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US$348.00
(Size: 60 µl)
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Datasheet SDS
NKX2-1 Antibody is a Rabbit Polyclonal antibody against NKX2-1. This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.
Research Articles on Thyroid Transcription Factor 1 (NKX2-1)
| Target | Thyroid Transcription Factor 1 (NKX2-1) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human NKX2-1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P43699 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DSA3, O14954, O14955, Q7KZF6, Q9BRJ8 |
| UniProt Entry Name | NKX21_HUMAN |
| Gene Symbol | NKX2-1 |
| GeneID | 7080 |
| NCBI Accession | NP_003308.1 |
| KEGG | hsa:7080 |
| String | 9606.ENSP00000346879 |
| Molecular Weight | Calculated MW: 38 kDa/41 kDa Observed MW: 39 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
