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Thyroid Transcription Factor 1 (NKX2-1) Antibody

Catalogue No: abx002227
Price: £120.00
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Thyroid Transcription Factor 1 (NKX2-1) Antibody

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NKX2-1 Antibody is a Rabbit Polyclonal antibody against NKX2-1. This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.

Target NKX2-1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human NKX2-1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P43699 (UniProt, ExPASy)
UniProt Secondary AC D3DSA3, O14954, O14955, Q7KZF6, Q9BRJ8
UniProt Entry Name NKX21_HUMAN
Gene Symbol NKX2-1
GeneID 7080
KEGG hsa:7080
String 9606.ENSP00000346879
Molecular Weight Calculated MW: 38 kDa, 41 kDa
Observed MW: Refer to Figures
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Thyroid Transcription Factor 1 (NKX2-1) Antibody

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