NK3 Homeobox 1 (NKX3-1) Antibody
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Catalogue No: abx034191
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US$326.25
(Size: 80 µl)
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Datasheet SDS
NKX3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. It Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Research Articles on NK3 Homeobox 1 (NKX3-1)
| Target | NK3 Homeobox 1 (NKX3-1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 118-145 amino acids from the Central region of human NKX3-1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q99801 (UniProt, ExPASy) |
| UniProt Secondary AC | O15465, Q9H2P4, Q9H2P5, Q9H2P6, Q9H2P7, Q9HBG0 |
| UniProt Entry Name | NKX31_HUMAN |
| Gene Symbol | NKX3-1 |
| KEGG | hsa:4824 |
| String | 9606.ENSP00000370253 |
| Molecular Weight | Calculated MW: 26.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse NKX3-1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |