Nitric Oxide Synthase, Brain (NOS1) Antibody

NOS1 Antibody is a Rabbit Polyclonal antibody against NOS1. The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.

Target	Nitric Oxide Synthase, Brain (NOS1)
Clonality	Polyclonal
Reactivity	Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human NOS1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P29475 (UniProt, ExPASy)
UniProt Secondary AC	E9PH30, O75713
UniProt Entry Name	NOS1_HUMAN
Gene Symbol	NOS1
GeneID	4842
NCBI Accession	NP_000611.1
KEGG	hsa:4842
String	9606.ENSP00000477999
Molecular Weight	Calculated MW: 161 kDa Observed MW: 160 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nitric Oxide Synthase, Brain (NOS1)

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