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NAD(P)H Dehydrogenase [quinone] 1 (NQO1) Antibody

Catalogue No: abx000532
Price: £120.00
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NQO1 Antibody is a Rabbit Polyclonal antibody against NQO1. This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Target NQO1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human NQO1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P15559 (UniProt, ExPASy)
UniProt Secondary AC B2R5Y9, B4DNM7, B7ZAD1, Q86UK1
Gene Symbol NQO1
GeneID 1728
Molecular Weight Calculated MW: 26 kDa, 27 kDa, 30 kDa
Observed MW: 31 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on NAD(P)H Dehydrogenase [quinone] 1 (NQO1) Antibody

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