Menu

Nuclear Receptor Subfamily 0 Group B Member 2 (NR0B2) Antibody

Catalogue No: abx001518
Price: £120.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Nuclear Receptor Subfamily 0 Group B Member 2 (NR0B2) Antibody Nuclear Receptor Subfamily 0 Group B Member 2 (NR0B2) Antibody Nuclear Receptor Subfamily 0 Group B Member 2 (NR0B2) Antibody Nuclear Receptor Subfamily 0 Group B Member 2 (NR0B2) Antibody

Available Options

* Size:




NR0B2 Antibody is a Rabbit Polyclonal antibody against NR0B2. The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function.

Target NR0B2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-257 of human NR0B2 (NP_068804.1).
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q15466 (UniProt, ExPASy)
UniProt Secondary AC F1D8P5, Q5QP36
UniProt Entry Name NR0B2_HUMAN
Gene Symbol NR0B2
GeneID 8431
NCBI Accession NP_068804.1
KEGG hsa:8431
String 9606.ENSP00000254227
Molecular Weight Calculated MW: 28 kDa
Observed MW: 28 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 2.04 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Nuclear Receptor Subfamily 0 Group B Member 2 (NR0B2) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good