Oxysterols Receptor LXR-Alpha (NR1H3) Antibody

Catalogue No: abx001753
Price: £120.00
(Size: 20 µl)
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NR1H3 Antibody is a Rabbit Polyclonal antibody against NR1H3. The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

Target NR1H3
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human NR1H3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13133 (UniProt, ExPASy)
UniProt Secondary AC A8K3J9, D3DQR1, Q8IW13, Q96H87
UniProt Entry Name NR1H3_HUMAN
Gene Symbol NR1H3
GeneID 10062
KEGG hsa:10062
String 9606.ENSP00000477707
Molecular Weight Calculated MW: 43 kDa, 45 kDa, 50 kDa
Observed MW: 45 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Oxysterols Receptor LXR-Alpha (NR1H3) Antibody

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