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Nuclear Receptor Subfamily 1 Group I Member 2 (NR1I2) Antibody

Catalogue No: abx001333
Price: £120.00
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Nuclear Receptor Subfamily 1 Group I Member 2 (NR1I2) Antibody Nuclear Receptor Subfamily 1 Group I Member 2 (NR1I2) Antibody

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NR1I2 Antibody is a Rabbit Polyclonal antibody against NR1I2. This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.

Target NR1I2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human NR1I2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O75469 (UniProt, ExPASy)
UniProt Entry Name NR1I2_HUMAN
Gene Symbol NR1I2
GeneID 8856
String 9606.ENSP00000336528
Molecular Weight Calculated MW: 39 kDa, 43 kDa, 45 kDa, 48 kDa, 49 kDa, 52 kDa, 53 kDa
Observed MW: 67 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Nuclear Receptor Subfamily 1 Group I Member 2 (NR1I2) Antibody

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