Nuclear Receptor Subfamily 2 Group C Member 2 (NR2C2) Antibody

NR2C2 Antibody is a Rabbit Polyclonal antibody against NR2C2. This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	Nuclear Receptor Subfamily 2 Group C Member 2 (NR2C2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human NR2C2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49116 (UniProt, ExPASy)
UniProt Secondary AC	A8K3H5, B6ZGT8, P55092
UniProt Entry Name	NR2C2_HUMAN
Gene Symbol	NR2C2
GeneID	7182
NCBI Accession	NP_003289.2
KEGG	hsa:7182
String	9606.ENSP00000483059
Molecular Weight	Calculated MW: 65 kDa Observed MW: 67 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nuclear Receptor Subfamily 2 Group C Member 2 (NR2C2)

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