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RNA Cytosine C(5)-Methyltransferase NSUN2 (NSUN2) Antibody
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Catalogue No: abx002471
Price:
US$203.00
(Size: 20 µl)
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NSUN2 Antibody is a Rabbit Polyclonal antibody against NSUN2. This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Research Articles on RNA Cytosine C(5)-Methyltransferase NSUN2 (NSUN2)
| Target | RNA Cytosine C(5)-Methyltransferase NSUN2 (NSUN2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 617-708 of human NSUN2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q08J23 (UniProt, ExPASy) |
| UniProt Entry Name | NSUN2_HUMAN |
| Gene Symbol | NSUN2 |
| GeneID | 54888 |
| OMIM | 610916 |
| NCBI Accession | NP_060225.4 |
| HGNC | 25994 |
| KEGG | hsa:54888 |
| Ensembl | ENSG00000037474 |
| String | 9606.ENSP00000264670 |
| Molecular Weight | Calculated MW: 86 kDa Observed MW: 100 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 2.32 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
