Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody

Catalogue No: abx001710
Price: £120.00
(Size: 20 µl)
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NTRK1 Antibody is a Rabbit Polyclonal antibody against NTRK1. This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Target NTRK1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human NTRK1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P04629 (UniProt, ExPASy)
UniProt Entry Name NTRK1_HUMAN
Gene Symbol NTRK1
GeneID 4914
KEGG hsa:4914
String 9606.ENSP00000431418
Molecular Weight Calculated MW: 77 kDa, 83 kDa, 86 kDa, 87 kDa
Observed MW: 110 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody

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