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Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody
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Catalogue No: abx001710
Price:
£120.00
(Size: 20 µl)
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NTRK1 Antibody is a Rabbit Polyclonal antibody against NTRK1. This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Research Articles on NTRK1
| Target | NTRK1 |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide of human NTRK1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04629 (UniProt, ExPASy) |
| UniProt Entry Name | NTRK1_HUMAN |
| Gene Symbol | NTRK1 |
| GeneID | 4914 |
| KEGG | hsa:4914 |
| String | 9606.ENSP00000431418 |
| Molecular Weight | Calculated MW: 77 kDa, 83 kDa, 86 kDa, 87 kDa Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
