Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody
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Catalogue No: abx001710
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US$348.00
(Size: 60 µl)
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Datasheet SDS
NTRK1 Antibody is a Rabbit Polyclonal antibody against NTRK1. This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Research Articles on Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1)
| Target | Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) |
| Research Area | Neuroscience |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human NTRK1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P04629 (UniProt, ExPASy) |
| UniProt Entry Name | NTRK1_HUMAN |
| Gene Symbol | NTRK1 |
| GeneID | 4914 |
| NCBI Accession | NP_002520.2 |
| KEGG | hsa:4914 |
| String | 9606.ENSP00000431418 |
| Molecular Weight | Calculated MW: 77 kDa/83 kDa/86 kDa/87 kDa Observed MW: 140 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
