NTRK2 (pY705) Antibody

NTRK2 (pY705) Antibody is a Rabbit Polyclonal antibody against NTRK2 (pY705). This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene.

Target	NTRK2 (pY705)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around Y705 of human TrkB.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16620 (UniProt, ExPASy)
UniProt Secondary AC	B1ANZ4, B4DFV9, Q16675, Q59GJ1, Q8WXJ5, Q8WXJ6, Q8WXJ7
UniProt Entry Name	NTRK2_HUMAN
Gene Symbol	NTRK2
GeneID	4915
NCBI Accession	NP_001018074.1
KEGG	hsa:4915
String	9606.ENSP00000277120
Molecular Weight	Calculated MW: 92 kDa Observed MW: 140 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NTRK2 (pY705)

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