Nucleoside Diphosphate Kinase A (NME1) Antibody

Nucleoside Diphosphate Kinase A (NME1) Antibody is a Rabbit Polyclonal antibody for the detection of NME1.

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Target	Nucleoside Diphosphate Kinase A (NME1)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	non-metastatic cells 1, protein (NM23A) expressed in
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P15531 (UniProt, ExPASy)
UniProt Secondary AC	Q6FGK3, Q86XQ2, Q9UDJ6
UniProt Entry Name	NDKA_HUMAN
Gene Symbol	NME1
GeneID	4830
OMIM	156490
HGNC	7849
KEGG	hsa:4830
Ensembl	ENSG00000239672
String	9606.ENSP00000337060
Molecular Weight	Observed MW: 17 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Nucleoside Diphosphate Kinase A (NME1)

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