Nuclear Mitotic Apparatus Protein 1 (NUMA1) Antibody

NUMA1 Antibody is a Rabbit Polyclonal antibody against NUMA1. This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

Target	Nuclear Mitotic Apparatus Protein 1 (NUMA1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human NUMA1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14980 (UniProt, ExPASy)
UniProt Secondary AC	H0YH75, Q14981, Q9BTE9
UniProt Entry Name	NUMA1_HUMAN
Gene Symbol	NUMA1
GeneID	4926
NCBI Accession	NP_006176.2
KEGG	hsa:4926
String	9606.ENSP00000377298
Molecular Weight	Calculated MW: 238 kDa Observed MW: 238 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	2.58 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nuclear Mitotic Apparatus Protein 1 (NUMA1)

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