NTF2-Related Export Protein 1 (NXT1) Antibody

The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein) and CRM1 (required for chromosome region maintenance) dependent pathways. It is found to stimulate the export of U1 snRNA in RAN and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.

Target	NTF2-Related Export Protein 1 (NXT1)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 85-111 amino acids from the C-terminal region of human NXT1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UKK6 (UniProt, ExPASy)
UniProt Entry Name	NXT1_HUMAN
String	9606.ENSP00000254998
Molecular Weight	Calculated MW: 15.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow NXT1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NTF2-Related Export Protein 1 (NXT1)

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