POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody

Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes.All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids.These include the POU homeodomain and the POU-specific domain.Both are required for DNA binding and are involved in protein-protein interactions.Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation.Oct4 is renowned as a transcription factor expressed by undifferentiated embryonic stem cells and embryonic germ cells.

Target	POU Class 5 Homeobox 1 / OCT4 (POU5F1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of OCT4 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q01860 (UniProt, ExPASy)
UniProt Entry Name	PO5F1_HUMAN
Gene Symbol	POU5F1
GeneID	5460
OMIM	164177
HGNC	9221
KEGG	hsa:5460
Ensembl	ENSG00000204531
String	9606.ENSP00000259915
Molecular Weight	39 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on POU Class 5 Homeobox 1 / OCT4 (POU5F1)

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