8-Oxoguanine DNA Glycosylase 1 (OGG1) Antibody
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Catalogue No: abx001848
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US$348.00
(Size: 60 µl)
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Datasheet SDS
OGG1 Antibody is a Rabbit Polyclonal antibody against OGG1. This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
Research Articles on 8-Oxoguanine DNA Glycosylase 1 (OGG1)
| Target | 8-Oxoguanine DNA Glycosylase 1 (OGG1) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human OGG1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O15527 (UniProt, ExPASy) |
| UniProt Entry Name | OGG1_HUMAN |
| Gene Symbol | OGG1 |
| GeneID | 4968 |
| NCBI Accession | NP_002533.1 |
| KEGG | hsa:4968 |
| String | 9606.ENSP00000306561 |
| Molecular Weight | Calculated MW: 22 kDa/36 kDa/38 kDa/39 kDa/40 kDa/45 kDa/47 kDa Observed MW: 36 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
