8-Oxoguanine DNA Glycosylase 1 (OGG1) Antibody

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Catalogue No: abx001848
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
OGG1 Antibody is a Rabbit Polyclonal antibody against OGG1. This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.

Target 8-Oxoguanine DNA Glycosylase 1 (OGG1)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-345 of human OGG1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O15527 (UniProt, ExPASy)
UniProt Entry Name OGG1_HUMAN
Gene Symbol OGG1
GeneID 4968
NCBI Accession NP_002533.1
KEGG hsa:4968
String 9606.ENSP00000306561
Molecular Weight Calculated MW: 39 kDa
Observed MW: 36 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 8-Oxoguanine DNA Glycosylase 1 (OGG1)


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