Mu-Type Opioid Receptor (OPRM1) Antibody
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Catalogue No: abx034237
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Mu-Type Opioid Receptor (OPRM1) Antibody is a Rabbit polyclonal against Mu-Type Opioid Receptor (OPRM1). Mu-Type Opioid Receptor (OPRM1) is the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin (see POMC, MIM 176830) and the enkephalins (see PENK, MIM 131330). The OPRM1 receptor is a membrane of the G protein-coupled receptor family (Bond et al., 1998 [PubMed 9689128]). There are at least 3 types of opioid receptors, mu, kappa (OPRK1; MIM 165196), and delta, each with a distinct pharmacologic profile.
Research Articles on Mu-Type Opioid Receptor (OPRM1)
| Target | Mu-Type Opioid Receptor (OPRM1) |
| Research Area | Neuroscience |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 161-187 amino acids from the Central region of Human Mu-Type Opioid Receptor (OPRM1). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35372 (UniProt, ExPASy) |
| UniProt Entry Name | OPRM_HUMAN |
| Gene Symbol | OPRM1 |
| GeneID | 4988 |
| KEGG | hsa:4988 |
| String | 9606.ENSP00000394624 |
| Molecular Weight | Calculated MW: 44.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat, Pig and Monkey OPRM1. |
| Concentration | 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |