Optineurin (OPTN) Antibody

Catalogue No: abx001525
Price: £120.00
(Size: 20 µl)
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Optineurin (OPTN) Antibody

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OPTN Antibody is a Rabbit Polyclonal antibody against OPTN. This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Target OPTN
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human OPTN.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q96CV9 (UniProt, ExPASy)
UniProt Entry Name OPTN_HUMAN
Gene Symbol OPTN
GeneID 10133
KEGG hsa:10133
String 9606.ENSP00000368022
Molecular Weight Calculated MW: 59 kDa, 65 kDa
Observed MW: 78 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Optineurin (OPTN) Antibody

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