Osteopetrosis-Associated Transmembrane Protein 1 (OSTM1) Antibody

This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.

Target	Osteopetrosis-Associated Transmembrane Protein 1 (OSTM1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q86WC4 (UniProt, ExPASy)
UniProt Secondary AC	E1P5E3, Q5R391, Q6PCA7, Q7RTW6, Q8NC29, Q8TC82, Q9Y2S9
UniProt Entry Name	OSTM1_HUMAN
Gene Symbol	OSTM1
KEGG	hsa:28962
String	9606.ENSP00000193322
Molecular Weight	Calculated MW: 37.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse OSTM1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Osteopetrosis-Associated Transmembrane Protein 1 (OSTM1)

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