p27Kip1 (pT198) Antibody

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Catalogue No: abx032019
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
p27Kip1 is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. This protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

Target p27Kip1 (pT198)
Clonality Polyclonal
Target Modification Thr198
Modification Phosphorylation
Reactivity Human
Tested Applications ELISA, DB
Host Rabbit
Recommended dilutions DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T198 of human p27Kip1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P46527 (UniProt, ExPASy)
UniProt Secondary AC Q16307, Q5U0H2, Q9BUS6
UniProt Entry Name CDN1B_HUMAN
KEGG hsa:1027
String 9606.ENSP00000228872
Molecular Weight Calculated MW: 22.1 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on p27Kip1 (pT198)


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