P2X Purinoceptor 6 (P2RX6) Antibody

The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.

Target	P2X Purinoceptor 6 (P2RX6)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 198-226 amino acids from the Central region of human P2RX6.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O15547 (UniProt, ExPASy)
UniProt Secondary AC	F6V3D7, Q32MB6, Q58F04, Q6IC33, Q9UL50
UniProt Entry Name	P2RX6_HUMAN
Gene Symbol	P2RX6
KEGG	hsa:9127
String	9606.ENSP00000416193
Molecular Weight	Calculated MW: 48.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on P2X Purinoceptor 6 (P2RX6)

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