P300 (pS1834) Antibody
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Catalogue No: abx031935
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CBP (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CBP can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
Research Articles on P300 (pS1834)
| Target | P300 (pS1834) |
| Clonality | Polyclonal |
| Target Modification | Ser1834 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, DB |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/10 - 1/50, DB: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human P300. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q09472 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AKC2 |
| UniProt Entry Name | EP300_HUMAN |
| NCBI Accession | NP_001420.2 |
| KEGG | hsa:2033 |
| String | 9606.ENSP00000263253 |
| Molecular Weight | Calculated MW: 264 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |