Prolyl 4-Hydroxylase Subunit Alpha-2 (P4HA2) Antibody

P4HA2 Antibody is a Rabbit Polyclonal antibody against P4HA2. This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Target	Prolyl 4-Hydroxylase Subunit Alpha-2 (P4HA2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 239-333 of human P4HA2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O15460 (UniProt, ExPASy)
UniProt Secondary AC	D3DQ85, D3DQ86, Q8WWN0
UniProt Entry Name	P4HA2_HUMAN
Gene Symbol	P4HA2
GeneID	8974
NCBI Accession	NP_004190.1
KEGG	hsa:8974
String	9606.ENSP00000384999
Molecular Weight	Calculated MW: 61 kDa Observed MW: 61 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Prolyl 4-Hydroxylase Subunit Alpha-2 (P4HA2)

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