Prolyl-4-Hydroxylase Alpha Polypeptide III (P4HA3) Antibody

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Target	Prolyl-4-Hydroxylase Alpha Polypeptide III (P4HA3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 274-303 amino acids from the Central region of human P4HA3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q7Z4N8 (UniProt, ExPASy)
UniProt Secondary AC	A0AV13, B4DUD3, Q5EBL3, Q5JPA9
UniProt Entry Name	P4HA3_HUMAN
Gene Symbol	P4HA3
KEGG	hsa:283208
String	9606.ENSP00000401749
Molecular Weight	Calculated MW: 61.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Prolyl-4-Hydroxylase Alpha Polypeptide III (P4HA3)

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