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Protein Disulfide-Isomerase (P4HB) Antibody

Catalogue No: abx000827
Price: £160.00
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Protein Disulfide-Isomerase (P4HB) Antibody Protein Disulfide-Isomerase (P4HB) Antibody Protein Disulfide-Isomerase (P4HB) Antibody

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P4HB Antibody is a Rabbit Polyclonal antibody against P4HB. This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

Target P4HB
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/100, IP: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human P4HB.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07237 (UniProt, ExPASy)
UniProt Secondary AC B2RDQ2, P30037, P32079, Q15205, Q6LDE5
UniProt Entry Name PDIA1_HUMAN
Gene Symbol P4HB
GeneID 5034
String 9606.ENSP00000327801
Molecular Weight Calculated MW: 57 kDa
Observed MW: 57 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Protein Disulfide-Isomerase (P4HB) Antibody

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