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p53 Phospho-Ser15 (p53 pS15) Antibody

Catalogue No: abx000156
Price: £120.00
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p53 Phospho-Ser15 (p53 pS15) Antibody p53 Phospho-Ser15 (p53 pS15) Antibody

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p53 (pS15) Antibody is a Rabbit Polyclonal antibody against p53 (pS15). This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).

Target p53 (pS15)
Clonality Polyclonal
Target Modification Ser15
Modification Phosphorylation
Reactivity Human
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S15 of human p53.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P04637 (UniProt, ExPASy)
UniProt Entry Name P53_HUMAN
Gene Symbol TP53
GeneID 7157
KEGG hsa:715
String 9606.ENSP00000269305
Molecular Weight Calculated MW: 23-43 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on p53 Phospho-Ser15 (p53 pS15) Antibody

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