V-Rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody

p65 Antibody is a Rabbit Polyclonal antibody against p65. NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Target	V-Rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/100 - 1/500, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 450-550 of human NF-kB p65/RelA.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q04206 (UniProt, ExPASy)
UniProt Secondary AC	Q6GTV1, Q6SLK1
Gene Symbol	RELA
GeneID	5970
NCBI Accession	NP_068810.3
Molecular Weight	Calculated MW: 60 kDa Observed MW: 65 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on V-Rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA)

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