P21 Protein Activated Kinase 2 (PAK2) Antibody

PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain.

Target	P21 Protein Activated Kinase 2 (PAK2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 192-222 amino acids from the N-terminal region of human PAK2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13177 (UniProt, ExPASy)
UniProt Secondary AC	Q13154, Q6ISC3
UniProt Entry Name	PAK2_HUMAN
KEGG	hsa:5062
String	9606.ENSP00000314067
Molecular Weight	Calculated MW: 58 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on P21 Protein Activated Kinase 2 (PAK2)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue