Par-6 Family Cell Polarity Regulator Alpha (PARD6A) Antibody

PARD6A Antibody is a Rabbit Polyclonal antibody against PARD6A. This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Target	Par-6 Family Cell Polarity Regulator Alpha (PARD6A)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PARD6A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NPB6 (UniProt, ExPASy)
UniProt Secondary AC	O14911, Q9NPJ7
UniProt Entry Name	PAR6A_HUMAN
Gene Symbol	PARD6A
GeneID	50855
String	9606.ENSP00000219255
Molecular Weight	Calculated MW: 37 kDa Observed MW: 47 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Par-6 Family Cell Polarity Regulator Alpha (PARD6A)

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