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E3 Ubiquitin-Protein Ligase Parkin (PRKN) Antibody
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Catalogue No: abx000921
Price:
£120.00
(Size: 20 µl)
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PRKN Antibody is a Rabbit Polyclonal antibody against PRKN. The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
Research Articles on E3 Ubiquitin-Protein Ligase Parkin (PRKN)
| Target | E3 Ubiquitin-Protein Ligase Parkin (PRKN) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human PARK2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60260 (UniProt, ExPASy) |
| UniProt Entry Name | PRKN_HUMAN |
| Gene Symbol | PRKN |
| GeneID | 5071 |
| KEGG | hsa:5071 |
| String | 9606.ENSP00000355865 |
| Molecular Weight | Calculated MW: 23 kDa, 30-51 kDa Observed MW: 52 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
