+44 (0) 1223 755950
+1 832 327 7413
E3 Ubiquitin-Protein Ligase Parkin (PRKN) Antibody
REQUEST MORE INFO
Catalogue No: abx032820
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function.
Research Articles on E3 Ubiquitin-Protein Ligase Parkin (PRKN)
| Target | E3 Ubiquitin-Protein Ligase Parkin (PRKN) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/250 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 111-140 amino acids from the N-terminal region of human Parkin. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60260 (UniProt, ExPASy) |
| UniProt Entry Name | PRKN_HUMAN |
| Gene Symbol | PRKN |
| GeneID | 5071 |
| OMIM | 168600 |
| HGNC | 8607 |
| KEGG | hsa:5071 |
| Ensembl | ENSG00000185345 |
| String | 9606.ENSP00000355865 |
| Molecular Weight | Calculated MW: 51.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |